International Journal of Education & Applied Sciences Research

International Journal of Education & Applied Sciences Research

Print ISSN : 2349 –4808

Online ISSN : 2349 –2899

Frequency : Continuous

Current Issue : Volume 3 , Issue 4
2016

SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF DENDRIMERS WITH INDAZOLE AS SURFACE UNITS AND MELAMINE AS CORE UNIT

*Mani Jayanthi , **Perumal Rajakumar

*,**Department of Organic Chemistry,  University of Madras, Guindy, Chennai

DOI : Page No : 28-43

Published Online : 2016-06-30

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Abstract

Dendrimers with indazole as surface units and melamine has core unit has been synthesized in good yields. The antimicrobial activities of the newly synthesized dendrimers were evaluated against four human pathogenic bacteria such as, E. coli, S. aureus, P. aeruginosa, B. subtilis  and one fungi C. albicans under in vitro conditions by “cup plate method”.

Keywords: Dendrimer, indazole, O-alkylation, LAH, antimicrobial